HPLC of Formula: 6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.
Chlorinated organic compounds are found in nearly every class of biomolecules. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. HPLC of Formula: 6334-18-5.
Vanam, Rateesh;Allam, Vijaykumar;Nerella, Srinivas;Gavaji, Brahmeshwari research published 《 Ru(II)- and Ru(IV)-dmso complexes catalyze efficient and selective aqueous-phase nitrile hydration reactions under mild conditions》, the research content is summarized as follows. A facile metal catalyst free, multi-component synthesis was established to afford tetrazolo dihydropyranochromenes I [R = H, 4-Me, 4-Br, etc.] and pyranochromeno pyridinediones II in high yields starting from 7-hydroxy-4-Me coumarin, aromatic aldehydes and malononitrile based on Green chem. principles. This protocol was applied to a wide range of aldehydes and demonstrates excellent functional group tolerance. Further, the synthesized compounds were screened in vitro against a panel of clin. relevant bacteria and fungi and found that these compounds possess moderate antimicrobial efficacy. The compound I [R = 2,3-di-Cl] and compound II [R = 2,3-di-Cl] were exhibited very impressive antimicrobial activity against four strains of bacteria and two strains of fungi. To know more about, their mechanism of action the lead compounds were virtually screened against a key microbial enzyme, tyrosyl-tRNA (TyrRS) synthetase and found that the compounds were bound with the enzyme through various interactions and thus able to inhibit the activity of the enzyme as evidenced by their binding energies. Further, the ADMET studies of the lead compounds were showed excellent favorable Druglikeness properties when they were tested with SwissADME program.
HPLC of Formula: 6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics