Chlorinated organic compounds are found in nearly every class of biomolecules. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Reference of 1878-65-5.
Wang, Hongyu;Liu, Chen-Fei;Song, Zhihui;Yuan, Mingbin;Ho, Yee Ann;Gutierrez, Osvaldo;Koh, Ming Joo research published 《 Engaging α-Fluorocarboxylic Acids Directly in Decarboxylative C-C Bond Formation》, the research content is summarized as follows. The readily accessible α-monofluoro carboxylic acids, which are conventionally difficult substrates for cross-coupling, undergo direct decarboxylative cross-coupling with sp2– and sp3-hybridized organohalides afforded a wide assortment of fluorinated products. Reactions were typically promoted by a combination of 1 mol % of an Ir-based photocatalyst and 2-15 mol % of a bipyridine-Ni complex, delivering products in up to 86% yield under blue LED light irradiation Concise synthesis of key therapeutic candidates underscores utility, complementarity and distinct advantages compared with existing methods. DFT calculations were used to rationalize the distinct reactivity of α-fluoro carboxylic acid substrates (vs nonfluorinated parent acids) under decarboxylation conditions.
1878-65-5, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., Reference of 1878-65-5
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics