Chloride substituents modify the physical properties of organic compounds in several ways. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Electric Literature of 1878-65-5.
Wang, Kang;Li, Shu-Sen;Wang, Jianbo research published 《 Cu(I)/Chiral Bisoxazoline-Catalyzed Enantioselective Doyle-Kirmse Reaction of Allenyl Sulfides with α-diazoesters》, the research content is summarized as follows. A Cu(I)-catalyzed enantioselective Doyle-Kirmse reaction of allenyl sulfides ArSCH=C=CH2(Ar = 2,3,5,6-tetrafluorophenyl, 2-ethoxy-3,5,6-trifluoropyridin-4-yl, 2,3,5,6-tetrafluoro-4-methylphenyl, etc.)and α-diazoesters R1C(=N2)COOR (R = t-Bu, 1-adamantyl, 2-phenylpropan-2-yl, 2-methylbutan-2-yl; R1 = Me, 4-fluorophenyl, naphthalen-2-yl, etc.) was reported, and provided an efficient synthetic route to enantio-enriched chiral tertiary homopropargylic sulfides R1C(SAr)(COOR)CH2CCH. This reaction features high enantioselectivities (up to 96% ee) and good functional group tolerance. The alkyl substituted α-diazoester has also been demonstrated as the efficient substrates in the asym. Doyle-Kirmse reaction. Mechanistic studies, including kinetic experiments, were conducted to gain insights into the details of the reaction pathway. The potential synthetic utility of this protocol has also been demonstrated.
Electric Literature of 1878-65-5, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., 1878-65-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics