Chlorinated organic compounds are found in nearly every class of biomolecules. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Category: chlorides-buliding-blocks.
Wang, Xia;Hu, Bo;Yang, Peng;Zhang, Qian;Li, Dong research published 《 Synthesis of vinyl sulfones through sulfonylation of styrenes with sulfonyl chlorides under metal-free conditions》, the research content is summarized as follows. A hypervalent iodine reagent-mediated sulfonylation of styrenes RR1C=CH2 (R = Ph, 4-methoxyphenyl, 3-methylphenyl, etc.; R1 = H, Ph) with sulfonyl chlorides R2SO2Cl (R2 = 4-methylphenyl, Ph, Et, thiophen-2-yl, etc.) was developed for the synthesis of vinyl sulfones RR1C=CHSO2R2. The reaction proceeded under metal-free, mild and neutral conditions without extra oxidants or bases. It also exhibited good air and moisture tolerance, broad substrate scope and high chemo-selectivity, affording the vinyl sulfones in moderate to good yields.
Category: chlorides-buliding-blocks, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics