Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Synthetic Route of 1878-65-5.
Wang, Xiaobin;Chai, Jianqi;Kong, Xiangyi;Jin, Fei;Chen, Min;Yang, Chunlong;Xue, Wei research published 《 Expedient discovery for novel antifungal leads: 1,3,4-Oxadiazole derivatives bearing a quinazolin-4(3H)-one fragment》, the research content is summarized as follows. Developing novel fungicide candidates are intensively promoted by the rapid emergences of resistant fungi that outbreak on agricultural production Aiming to discovery novel antifungal leads, a series of 1,3,4-oxadiazole derivatives bearing a quinazolin-4(3H)-one fragment were constructed for evaluating their inhibition effects against phytopathogenic fungi in vitro and in vivo. Systematically structural optimizations generated the bioactive mol. I32 (I) that was identified as a promising inhibitor against Rhizoctonia solani with the in vivo preventative effect of 58.63% at 200μg/mL. The observations that were captured by SEM and transmission electron microscopy demonstrated that the bioactive mol. I32 could induce the sprawling growth of hyphae, the local shrinkage and rupture on hyphal surfaces, the extreme swelling of vacuoles, the striking distortions on cell walls, and the reduction of mitochondria numbers The above results provided an indispensable complement for the discovery of antifungal lead bearing a quinazolin-4(3H)-one and 1,3,4-oxadiazole fragment.
Synthetic Route of 1878-65-5, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., 1878-65-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics