The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Safety of 3-Bromobenzenesulfonyl chloride.
Wang, Xucheng;Cheng, Yao;Wang, Lingyan;Wang, Rui;Zhang, Min;Yuan, Yaofeng;Hu, Jianda;Wang, Wenfeng research published 《 Synthesis, crystal structure and negative hyperconjugation study of quinoxaline derivatives containing piperazine》, the research content is summarized as follows. The neg. hyperconjugation (NHC) of sp2 and sp3 hybrid nitrogen atoms was studied based on the calculation of quinoxaline derivatives I (X = 2-Br, 3-Br, 4-Br) containing piperazine moiety. The energy level, electronic d. and spatial position of acceptor orbital are all important factors of NHC. NHC of nitrogen atom does not limit in the case that the σ*-acceptor orbital is in the anti-staggered position of donor orbital, but it will switch off when nitrogen atom loses its lone pair electron. These results are proved by the crystal structure and the calculation of vibration frequencies. At last, two quinoxaline derivatives Isynthesized in this work show good anticancer activities against leukemia cell lines.
2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Safety of 3-Bromobenzenesulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics