Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Safety of Chloro(1,5-cyclooctadiene)iridium(I) dimer.
Yang, Jianping;Massaro, Luca;Krajangsri, Suppachai;Singh, Thishana;Su, Hao;Silvi, Emanuele;Ponra, Sudipta;Eriksson, Lars;Ahlquist, Maarten S. G.;Andersson, Pher G. research published 《 Combined Theoretical and Experimental Studies Unravel Multiple Pathways to Convergent Asymmetric Hydrogenation of Enamides》, the research content is summarized as follows. A highly efficient convergent asym. hydrogenation of E/Z mixtures of enamides catalyzed by N,P-iridium complexes supported by mechanistic studies was reported. It was found that reduction of the olefinic isomers (E and Z geometries) produced chiral amides with the same absolute configuration (enantioconvergent hydrogenation). This allowed the hydrogenation of a wide range of E/Z mixtures of trisubstituted enamides with excellent enantioselectivity (up to 99% ee). A detailed mechanistic study using deuterium labeling and kinetic experiments revealed two different pathways for the observed enantioconvergence. For α-aryl enamides, fast isomerization of the double bond took place, and the overall process resulted in kinetic resolution of the two isomers. For α-alkyl enamides, no double bond isomerization was detected, and competition experiments suggested that substrate chelation was responsible for the enantioconvergent stereochem. outcome. DFT calculations were performed to predict the correct absolute configuration of the products and strengthen the proposed mechanism of the iridium-catalyzed isomerization pathway.
Safety of Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
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Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics