Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Name: 4-Fluorobenzene-1-sulfonyl chloride.
Yang, Lingyun;Sun, Yi;He, Linghui;Fan, Yujia;Wang, Tao;Luo, Jin research published 《 Synthesis and herbicidal activity of novel 1,2,4-triazole derivatives containing fluorine, phenyl sulfonyl and pyrimidine moieties》, the research content is summarized as follows. In this study, 4-amino-2-(alkylthio)-6-(methylthio) pyrimidine-5-carbonitrile I was employed as the starting material to synthesize a novel series of 1,2,4-triazole derivatives containing fluorine, Ph sulfonyl and pyrimidine moieties I (R1 = Et, n-Pr, n-Bu; R2 = H, 4-F, 4-Cl, etc.; R3 = H, Me; R4 = Me, OMe, Cl, etc.). The preliminary bioassay indicated that many newly synthesized compounds exhibited moderate to good herbicidal activities against the monocotyledons (Echinochloa crusgalli, Sorghum bicolor) and dicotyledons (Raphanus sativus, Brassica campestris, Cucumis sativus, and Medicago sativa) at the concentrations of 100 mg·L-1 and 10 mg·L-1. Especially, compound I displayed good herbicidal activity, with 100% inhibition against Brassica campestris, Cucumis sativus, and Medicago sativa at a concentration of 100 mg·L-1.
349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.
4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.
4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., Name: 4-Fluorobenzene-1-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics