Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Application In Synthesis of 3900-89-8.
Zhang, Qijing;Lei, Hao;Zhou, Cong-Ying;Wang, Chengming research published 《 Construction of N-Polyheterocycles by N-Heterocyclic Carbene Catalysis via a Regioselective Intramolecular Radical Addition/Cyclization Cascade》, the research content is summarized as follows. N-Polyheterocycles I [R1 = H, 11-Me, 11-methoxy; R2 = H, 4-methyl; R3 = Me, Bu, benzyl; R4 = Me; R5 = Me, Et, ethoxycarbonyl] were rapidly accessed by N-heterocyclic carbene (NHC) catalysis through regioselective sequential radical addition/cyclization in the absence of any metals or oxidants. The transformation occurs under mild conditions and enjoys a wide substrate scope with excellent functional group compatibility. Furthermore, a gram-scale synthesis was also conducted. Preliminary mechanistic studies reveal the potential involvement of an NHC radical cation intermediate.
Application In Synthesis of 3900-89-8, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., 3900-89-8.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics