On June 3, 2016, Castanheiro, Thomas; Suffert, Jean; Gulea, Mihaela; Donnard, Morgan published an article.Application of 14602-86-9 The title of the article was Aerobic Copper-Mediated Domino Three-Component Approach to 2-Aminobenzothiazole Derivatives. And the article contained the following:
N-(2-Benzothiazolyl)amides were prepared by the three-component reactions of 2,2′-diaminodiaryl disulfides (or the hydrochloride of an aminotrifluoromethylbenzenethiol), copper cyanide, and acyl, dimethylthiocarbamoyl, or L-menthyloxyformyl chlorides, Boc anhydride, and Ph isocyanate using an oxidative copper-mediated S-cyanation as a key step followed by cyclization and acylation. The reaction proceeds by a mechanism involving an intermol. migration of the acyl group, as scrambling of acyl groups in reactions of acylaminophenyl disulfides was found. The structure of N-(2-benzothiazolyl)-2,5-difluorobenzamide was determined by X-ray crystallog. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Application of 14602-86-9
The Article related to benzothiazolyl amide chemoselective preparation, copper cyanide aminoaryl disulfide thiol acyl chloride chemoselective reaction, oxidative cyanation cyclization acylation reaction copper cyanide aminoaryl disulfide, fluorobenzamide benzothiazolyl mol crystal structure and other aspects.Application of 14602-86-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics