On December 1, 2017, Patel, Krishnakant; Song, Fengling; Andreana, Peter R. published an article.HPLC of Formula: 14602-86-9 The title of the article was Synthesis of substrate analogues as potential inhibitors for Mycobacterium tuberculosis enzyme MshC. And the article contained the following:
Mycothiol cysteine ligase (MshC) is a key enzyme in the mycothiol (MSH) biosynthesis and a promising target for developing new anti-mycobacterial compounds Herein, we report on the synthesis of substrate analogs, as potential inhibitors, for the MshC enzyme. The target mols. were synthesized employing a Schmidt glycosylation strategy using an enantiomerically pure inositol acceptor and 2-deoxy trichloroacetimidate glycosyl donors with glycosylation yields greater than 70% and overall yields >5%. The inositol acceptor was obtained via chiral resolution of (±)-myo-inositol. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).HPLC of Formula: 14602-86-9
The Article related to mycothiol cysteine ligase mshc mycobacterium substrate analog inhibitor tuberculosis, chiral resolution, glucosamine inositol, mshc, mycothiol, substrate analogues, tuberculosis and other aspects.HPLC of Formula: 14602-86-9
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