On July 22, 2022, Verdhi, Lenin Kumar; Fridman, Natalia; Szpilman, Alex M. published an article.Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate The title of the article was Copper- and Chiral Nitroxide-Catalyzed Oxidative Kinetic Resolution of Axially Chiral N-Arylpyrroles. And the article contained the following:
A readily prepared C2-sym., α-hydrogen-substituted chiral hydroxylamine served as a precatalyst to generate a chiral nitroxide in situ. This chiral nitroxide catalyst in combination with a copper co-catalyst functions as an oxidant for an unprecedented enantioselective oxidative kinetic resolution (OKR) of racemic axially chiral N-arylpyrrole alcs. using atm. oxygen as an environmentally friendly terminal oxidant. The OKR process provided the axially chiral N-arylpyrroles in er up to 3.5:96.5 and with s factors up to 24. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate
The Article related to racemic arylpyrrole alc copper catalyst oxidative kinetic resolution, arylpyrrole alc enantioselective green preparation, aryl pyrrole aldehyde enantioselective green preparation and other aspects.Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics