On November 30, 1999, Waterhouse, Ian published an article.Safety of 1,5-Dichloro-3-methoxy-2-nitrobenzene The title of the article was Synthesis of deuterium labelled 4′-hydroxydiclofenac. And the article contained the following:
Diclofenac is a potentially useful substrate for the study of drug-drug interactions caused by modulation of the activity of specific isoforms of cytochrome P 450. The synthesis of deuterium labeled 4′-hydroxydiclofenac I, a deuterated analog of a metabolite of diclofenac, is described for use as an internal standard in LC-MS-MS studies. The experimental process involved the reaction of 1,5-Dichloro-3-methoxy-2-nitrobenzene(cas: 74672-01-8).Safety of 1,5-Dichloro-3-methoxy-2-nitrobenzene
The Article related to deuterium labeled hydroxydiclofenac preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Safety of 1,5-Dichloro-3-methoxy-2-nitrobenzene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics