On August 21, 2020, Sun, Guodong; Wang, Zhongqing; Luo, Zhonghua; Lin, Yicao; Deng, Zhuofei; Li, Ridong; Zhang, Jiancun published an article.Application of 14602-86-9 The title of the article was Design, Synthesis, and Resolution of Spirocyclic Bisoxindole-Based C2-Symmetric Diols. And the article contained the following:
A new type of spirocyclic bisoxindole-based C2-sym. diols (SBIDOLs) was designed and synthesized. A series of racemic SBIDOL derivatives were readily synthesized from com. available 2-halo-5-methoxyanilines (X = Cl or Br) through N-mono alkylation, acylation, oxidation, double intramol. Friedel-Crafts reaction, and demethylation reactions. The optical resolution of racemic SBIDOL was achieved via fractional crystallization of their bis-L-menthoxycarboxylates. Further modifications of SBIDOLs were investigated, leading to 5,5′-diaryl SBIDOL derivatives through Pd-catalyzed Suzuki coupling and DM-SBIDOL 12 by Pd/C-catalyzed hydrogenative dechlorination reactions. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Application of 14602-86-9
The Article related to halo methoxyaniline alkylation acylation oxidation friedel crafts demethylation resolution, spirocyclic bisoxindole diol preparation, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Application of 14602-86-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics