Chen, Xiulei; Zhou, Zhen; Li, Zhong; Xu, Xiaoyong published an article in 2020, the title of the article was Synthesis and nematicidal activities of 1,2,3-benzotriazin-4-one containing 4,5-dihydrothiazole-2-thiol derivatives against Meloidogyne incognita.Synthetic Route of 89-77-0 And the article contains the following content:
A series of novel 1,2,3-benzotriazin-4-one derivatives containing 4,5-dihydrothiazole-2-thiol I (R = H, 5-OMe, 7-F, 8-NO2, etc.) was synthesized. The bioassay results showed that compounds I (R = 7-OMe, 6-NO2, 7-Cl (A)) exhibited good control efficacy against the cucumber root-knot nematode disease caused by Meloidogyne incognita at the concentration of 10.0 mg L-1 in vivo. Compound (A) showed excellent nematicidal activity with inhibition 68.3% at a concentration of 1.0 mg L-1. It suggested that the structure of 1,2,3-benzotriazin-4-one containing 4,5-dihydro-thiazole-2-thiol could be optimized further. The experimental process involved the reaction of 2-Amino-4-chlorobenzoic acid(cas: 89-77-0).Synthetic Route of 89-77-0
The Article related to benzotriazinone dihydrothiazole thiol preparation nematocidal activity, Heterocyclic Compounds (More Than One Hetero Atom): Triazines and other aspects.Synthetic Route of 89-77-0
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