On January 31, 2013, Saha, Ishita; Kumar, Gopinatha Suresh published an article.Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the article was Phenazinium dyes methylene violet 3RAX and indoine blue bind to DNA by intercalation: Evidence from structural and thermodynamic studies. And the article contained the following:
The structural and energetic aspects of the interaction of two important phenazinium dyes methylene violet 3RAX and indoine blue with DNA were studied by spectroscopic and thermochem. techniques. The binding affinity values of both the dyes were of the order of 105 M-1 but methylene violet 3RAX bound to DNA more strongly. Both dyes bound DNA by intercalation but methylene violet 3RAX bound stronger than indoine blue. The DNA binding of both the dyes was exothermic and favored by a small neg. enthalpy and pos. entropy contributions. The effect of ionic strength indicated that electrostatic attraction is an important component of the dye-DNA interaction although the major contribution comes from hydrophobic forces. The temperature dependence of enthalpy changes yielded neg. heat capacity value which was higher for methylene violet 3RAX compared to indoine blue suggesting higher contribution from hydrophobic forces in the interaction of the former. Enthalpy-entropy compensation phenomenon was observed for the binding of both dyes to DNA. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride
The Article related to phenazinium dye methylene violet 3rax indoine blue dna intercalation, General Biochemistry: Nucleic Acids and Their Constituents and other aspects.Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics