Tabero, Andrea et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2020 |CAS: 35444-44-1

The Article related to bodipy lipid droplet target pdt photosensitize imaging, Radiation Biochemistry: Disease Diagnosis and Therapy and other aspects.Category: chlorides-buliding-blocks

Tabero, Andrea; Garcia-Garrido, Fernando; Prieto-Castaneda, Alejandro; Palao, Eduardo; Agarrabeitia, Antonia R.; Garcia-Moreno, Inmaculada; Villanueva, Angeles; de la Moya, Santiago; Ortiz, Maria J. published an article in 2020, the title of the article was BODIPYs revealing lipid droplets as valuable targets for photodynamic theragnosis.Category: chlorides-buliding-blocks And the article contains the following content:

Endowing BODIPY PDT agents with the ability to probe lipid droplets is demonstrated to boost their phototoxicity, allowing the efficient use of highly fluorescent dyes (poor ROS sensitizers) as phototoxic agents. Conversely, this fact opens the way to the development of highly bright ROS photosensitizers for performing photodynamic theragnosis (fluorescence bioimaging and photodynamic therapy) from a single simple agent. On the other hand, the noticeable capability of some of the reported dyes to probe lipid droplets in different cell lines under different conditions reveals their use as privileged probes for advancing the study of interesting lipid droplets by fluorescence microscopy. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Category: chlorides-buliding-blocks

The Article related to bodipy lipid droplet target pdt photosensitize imaging, Radiation Biochemistry: Disease Diagnosis and Therapy and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics