Alp, Mehmet published the artcileSynthesis and antiparasitic and antifungal evaluation of 2′-arylsubstituted-1H,1’H-[2,5′]bisbenzimidazolyl-5-carboxamidines, Name: 4-(4-Chlorophenoxy)benzaldehyde, the main research area is phenylenediamine benzimidazolyl condensation aldehyde aryl; benzimidazole bis aryl amidino preparation antiparasitic antifungal activity.
A series of 2′-aryl-1H,1’H-[2,5′]-bisbenzimidazolyl-5-carboxamidines I (e.g., R1R2 = benzo, R3 = R4 = H) were prepared in a six-step process starting from 4-amino-3-nitrobenzonitrile. The antiparasitic activity against Trypanosoma brucei rhodesiense (T.b.r.), Plasmodium falciparum (P.f.), Leishmania donovani (L.d.) and Trypanosoma cruzi (T.c.) and antifungal activity against Candida albicans and Candida krusei were evaluated in vitro. Several compounds showed promising in vitro activity against T.b.r., P.f. and C. albicans and had superior activity against P.f. as compared to chloroquine.
European Journal of Medicinal Chemistry published new progress about Aromatic diamines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 61343-99-5 belongs to class chlorides-buliding-blocks, name is 4-(4-Chlorophenoxy)benzaldehyde, and the molecular formula is C13H9ClO2, Name: 4-(4-Chlorophenoxy)benzaldehyde.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics