Asadollahi-Baboli, M. published the artcileStraightforward MIA-QSTR evaluation of environmental toxicities of aromatic aldehydes to Tetrahymena pyriformis, Recommanded Product: 6-Chloro-2-fluoro-3-methylbenzaldehyde, the main research area is quant structure activity relationship aromatic aldehyde Tetrahymena ecotoxicity.
Aldehydes are toxic environmental contaminants which cause severe health hazards. There is a growing need by industries and regulatory agencies for the development of tools able to assess the potential hazardous effects of chems. on living organisms. In this background, multivariate image anal. combined with quant. structure-toxicity relationships (MIA-QSTR) was used to evaluate the toxicity of aromatic aldehydes to Tetrahymena pyriformis. The techniques of genetic algorithm-partial least squares (GA-PLS) were applied effectively as MIA descriptor selection and mapping tools. In MIA-QSTR evaluation, pixels of 2D images of chem. structures could be used to recognize physicochem. information and predict changes in the toxicities. The resulting MIA-QSTR explains 90.3% leave-one-out predicted variance and 93.1% external predicted variance. The MIA-QSTR/GA-PLS performances were validated using various evaluation techniques such as cross-validation, applicability domain and Y-scrambling procedures, suggesting that the present methodol. together with mechanistic interpretation may be useful to evaluate toxicity, safety and risk assessment of toxic environmental contaminants.
SAR and QSAR in Environmental Research published new progress about Ecotoxicity. 286474-59-7 belongs to class chlorides-buliding-blocks, name is 6-Chloro-2-fluoro-3-methylbenzaldehyde, and the molecular formula is C8H6ClFO, Recommanded Product: 6-Chloro-2-fluoro-3-methylbenzaldehyde.
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics