Liu, Zong-ying published the artcileSynthesis and evaluation of 1-(benzo[b]thiophen-2-yl)ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotor, Quality Control of 93118-03-7, the main research area is benzothiophenyl ethanone derivative preparation BMP2 promotor antiosteoporosis agent.
A novel series of 1-(benzo[b]thiophen-2-yl)ethanone analogs were prepared and evaluated for enhancing BMP-2 expression. Some compounds exhibited potent effect for enhancing BMP-2 expression. Compounds I and II produced a dose-dependent increase on bone histol. and histomorphometry, and effectively reduced bone defects induced by ovariectomy in an ovariectomized rat model (OVX).
Bioorganic & Medicinal Chemistry Letters published new progress about Antiosteoporotic agents. 93118-03-7 belongs to class chlorides-buliding-blocks, name is 2-Chloro-3-(trifluoromethyl)benzaldehyde, and the molecular formula is C8H4ClF3O, Quality Control of 93118-03-7.
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Chlorides – an overview | ScienceDirect Topics