Peng, Jianwen published the artcileSynthesis of Polysubstituted 3-Amino Pyrroles via Palladium-Catalyzed Multicomponent Reaction, Safety of 4-Chloro-2-fluoroiodobenzene, the main research area is polysubstituted aminopyrrole preparation; palladium catalyst three component tandem reaction; phenyldihydropyrroloindole preparation.
A novel approach for the synthesis of polysubstituted 3-amino pyrroles via palladium-catalyzed three-component tandem reaction was developed. The procedure constructs various polysubstituted 3-amino pyrroles, e.g. I, with moderate to excellent yields under mild reaction conditions with assembly efficiency, readily available starting materials, and good functional group tolerance. Furthermore, this process was successfully applied to the synthesis of different 3-phenyl-1,4-dihydropyrrolo[3,2-b]indole derivatives via an intramol. Buchwald-Hartwig cross-coupling reaction in two steps.
Journal of Organic Chemistry published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Safety of 4-Chloro-2-fluoroiodobenzene.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics