Shen, Chaoren published the artcilePalladium-Catalyzed Carbonylative Four-Component Synthesis of Thiochromenones: The Advantages of a Reagent Capsule, Safety of 4-Chloro-2-fluoroiodobenzene, the main research area is four component reaction fluoroiodobenzene phenylacetylene carbonylative palladium catalyst; thiochromenone preparation; carbonylation; multicomponent reactions; palladium catalysis; thiochromenones.
Multicomponent reactions, especially those involving four or even more reagents, have been a long-standing challenge because of the issues associated with balancing reactivity, selectivity, and compatibility. Herein, we demonstrate how the use of a reagent capsule provides straightforward access to synthetically valuable thiochromenone derivatives by a palladium-catalyzed carbonylative four-component reaction. To the best of our knowledge, this is the first example of applying a capsule to prevent catalyst poisoning and undesired side reactions of the multicomponent reaction.
Angewandte Chemie, International Edition published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Safety of 4-Chloro-2-fluoroiodobenzene.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics