Laha, Joydev K. published the artcileScope of Successive C-H Functionalizations of the Methyl Group in 3-Picolines: Intramolecular Carbonylation of Arenes to the Metal-Free Synthesis of 4-Azafluorenones, HPLC of Formula: 480438-56-0, the main research area is picoline aryl oxidant intramol carbonylation; azafluorenone preparation.
A transition-metal-free, t-BuOOH mediated intramol. carbonylation of arenes in 2-aryl-3-picolines via oxidative C-H functionalizations of the Me group has been developed, providing an expedient synthesis of 4-azafluorenones I [R = 7-MeO, 7-OCF3, 6,7-Cl2, 6-Cl-7-OPr-i, 7,8-(OMe)2, etc] . Distinct from the current literature wherein methylarenes have been used as acylating agents, 2-aryl-3-picolines in this study are transformed into aldehydes, which give 4-azafluorenones upon rapid intramol. acylation. The study demonstrates the first example of intramol. carbonylation of arenes utilizing a Me group as latent carbonyl functionality.
Organic Letters published new progress about C-H bond activation (oxidative). 480438-56-0 belongs to class chlorides-buliding-blocks, name is 3-Chloro-4-isopropoxyphenylboronic acid, and the molecular formula is C9H12BClO3, HPLC of Formula: 480438-56-0.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics