Cankarova, Nadezda published the artcileNovel preloaded resins for solid-phase biotinylation of carboxylic acids, Product Details of C7H3ClFNO4, the main research area is carboxylic acid solid phase biotinylation.
Use of solid-phase synthesis for the derivatization of carboxylic acids with biotinylated spacers consisting of ethylenoxy units is described. An aminomethylated resin provided with an acid-labile aldehyde linker is used as the polymer support and three different systems with a reactive amino group are introduced. Acylation of each system was tested with a set of model carboxylic acids and afforded crude products of excellent purity. The preloaded resins are similar to the Biotin-PEG-NovaTagTM resin but offer several advantages including simple elongation of the spacer arm. The protocols described represent a very efficient way of modifying compounds to obtain ligands for affinity chromatog. studies.
Tetrahedron Letters published new progress about Affinity chromatography. 35112-05-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoro-5-nitrobenzoic acid, and the molecular formula is C7H3ClFNO4, Product Details of C7H3ClFNO4.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics