Telvekar, Vikas N. published the artcileNovel 2-(2-(4-aryloxybenzylidene) hydrazinyl)benzothiazole derivatives as anti-tubercular agents, Related Products of chlorides-buliding-blocks, the main research area is aryloxy benzylidene hydrazinyl benzothiazole preparation antitubercular.
A series of structurally novel, substituted 2-(2-(4-aryloxybenzylidene) hydrazinyl)benzothiazole derivatives incorporating 2-hydrazinyl benzothiazole and 4-(aryloxy)benzaldehyde were designed and synthesized using mol. hybridization approach. All the synthesized compounds exhibited promising activity (MIC 1.5-29.00 μg/mL) against Mycobacterium tuberculosis H37Rv strains of using REMA. Five of the evaluated compounds exhibit MIC <3.0 μg/mL. Compound (E)-6-chloro-2-(2-(4-(2,4-dichlorophenoxy)benzylidene)hydrazinyl) benzothiazole showed MIC of 1.5 μg/mL. Thus, this compound could act as a potential lead for further development of new anti-tubercular drugs. Bioorganic & Medicinal Chemistry Letters published new progress about Mycobacterium tuberculosis. 61343-99-5 belongs to class chlorides-buliding-blocks, name is 4-(4-Chlorophenoxy)benzaldehyde, and the molecular formula is C13H9ClO2, Related Products of chlorides-buliding-blocks.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics