Desai, Ranjit C. published the artcile5-Aryl thiazolidine-2,4-diones: discovery of PPAR dual α/γ agonists as antidiabetic agents, Category: chlorides-buliding-blocks, the main research area is thiazolidinedione derivative preparation structure activity peroxisome proliferator receptor antidiabetic.
A novel series of 5-aryl thiazolidine-2,4-diones based dual PPARα/γ agonists was identified. A number of highly potent and orally bioavailable analogs were synthesized. Efficacy study results of some of these analogs in the db/db mice model of type 2 diabetes showed them superior to rosiglitazone in correcting hyperglycemia and hypertriglyceridemia.
Bioorganic & Medicinal Chemistry Letters published new progress about Antidiabetic agents. 61343-99-5 belongs to class chlorides-buliding-blocks, name is 4-(4-Chlorophenoxy)benzaldehyde, and the molecular formula is C13H9ClO2, Category: chlorides-buliding-blocks.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics