Wu, Junchen published the artcileA Molecular Peptide Beacon for the Ratiometric Sensing of Nucleic Acids, Name: Pyrene-2-carboxylic acid, the main research area is mol peptide beacon preparation ratiometry fluorescence sensor DNA.
A pyrene-functionalized cationic oligopeptide I efficiently binds to double-stranded DNA, as shown by different spectrophotochem. studies. Upon binding, the conformation of I changes from a folded to an extended form, which leads to a distinct change in the fluorescence properties. Thus, I functions as a mol. peptide beacon, and as it is easily taken up by cells, I can also be used for imaging of nucleic acids within cells.
Journal of the American Chemical Society published new progress about Biological uptake. 36428-96-3 belongs to class chlorides-buliding-blocks, name is Pyrene-2-carboxylic acid, and the molecular formula is C17H10O2, Name: Pyrene-2-carboxylic acid.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics