Crawford, R. L. published the artcileDegradation of methoxylated benzoic acids by a Nocardia from a lignin-rich environment. Significance to lignin degradation and effect of chloro substituents, Safety of 3-Chloro-4-hydroxy-5-methoxybenzoic acid, the main research area is methyl benzoate demethylation Nocardia; lignin degradation actinomycete benzoate derivative; anisate vanillate demethylation Nocardia.
N. corallina A81 from a lignin-rich environment demethylated p-anisic acid to p-hydroxybenzoic acid and isovanillic acid. It dimethylated veratric acid to a mixture of vanillic and isovanillic acids, which were both demethylated to protocatechuic acid which undergoes ring cleavage to muconic acid. An o-chloro substituent on the benzene ring hinders both demethylation and ring opening. o-Hydroxylation of p-methoxybenzoic acid to isovanillic acid was unaffected by a Cl ortho to the Me group. Though N. corallina was able to use various aromatic compounds that are structurally related to lignin, no structural changes in isolated lignin were detected.
Applied Microbiology published new progress about Nocardia. 62936-23-6 belongs to class chlorides-buliding-blocks, name is 3-Chloro-4-hydroxy-5-methoxybenzoic acid, and the molecular formula is C8H7ClO4, Safety of 3-Chloro-4-hydroxy-5-methoxybenzoic acid.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics