Hradil, Pavel published the artcileSynthesis, NMR spectra and X-ray data of chloro and dichloro derivatives of 3-hydroxy-2-phenylquinolin-4(1H)-ones and their cytostatic activity, Application of 2-Amino-3,6-dichlorobenzoic acid, the main research area is hydroxy phenylquinolinone preparation cytostatic agent.
As known, some derivatives of quinolin-4(1H)-one possess interesting biol. properties. The biol. and cytostatic activity of 2-substituted 3-hydroxyquinolin-4(1H)-ones has not been reported yet. In this paper the synthesis of a series of chloro and dichloro 2-phenyl-3-hydroxyquinolin-4(1H)-ones and their characterization by NMR spectra and X-ray data is described. Their cytostatic properties have been evaluated and the results are reported.
Journal of Heterocyclic Chemistry published new progress about Cyclization. 3032-32-4 belongs to class chlorides-buliding-blocks, name is 2-Amino-3,6-dichlorobenzoic acid, and the molecular formula is C7H5Cl2NO2, Application of 2-Amino-3,6-dichlorobenzoic acid.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics