Kas’yan, A. O. published the artcileDerivatives of exo-5-Aminomethyl-endo-5-methylbicyclo-[2.2.1]hept-2-ene and exo-5-Aminomethyl-endo-5-methyl-exo-2,3-epoxybicyclo[2.2.1]heptane, Formula: C7H6ClFO2S, the main research area is methylbicycloheptenemethanamine aminomethylbicycloheptene preparation; aminomethylepoxybicycloheptane oxatricyclooctanemethanamine preparation; rotational conformational barrier methylbicycloheptenemethanamine oxatricyclooctanemethanamine preparation.
(1R,2S,4R)-rel-2-methylbicyclo[2.2.1]hept-5-ene-2-methanamine (exo-isomer, I) and (1R,2R,4S,5S,6S)-rel-6-methyl-3-oxatricyclo[3.2.1.02,4]octane-6-methanamine were synthesized, and their geometric parameters and conformational properties, in particular the barriers to rotation of the aminomethyl fragment about the exocyclic C5-C bond, were studied by the mol.-mechanics method (MMX) and compared with those found for structurally related to I. The title compounds were brought into reactions with electrophilic reagents: arenesulfonyl chlorides, isocyanates, and isothiocyanates. The neurotropic activity of two compounds thus prepared was mentioned.
Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) published new progress about Conformation. 7079-48-3 belongs to class chlorides-buliding-blocks, name is 4-Fluoro-2-methylbenzene-1-sulfonyl chloride, and the molecular formula is C7H6ClFO2S, Formula: C7H6ClFO2S.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics