Shchetinina, V. N. published the artcileEffect of decamethoxine on the integrity of cytoplasmic membranes of gram-positive and gram-negative microorganisms, Name: N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, the publication is Mikrobiologicheskii Zhurnal (1978-1993) (1990), 52(3), 24-8, database is CAplus.
Decamethoxine increased the membrane permeability of Pseudomonas aeruginosa, Escherichia coli, and Micrococcus lysodeikticus. Viability decreased and dehydrogenase activity was inhibited. Aspartate and alanine aminotransferases were not inhibited by decamethoxine, and activity even increased. Decamethoxine lysed the protoplasts of these bacteria. At high decamethoxine concentrations (>500 μg/mL for P. aeruginosa and >200 μ/mL for E. coli) the outflow of components from these gram-neg. bacteria ceased; this may be associated with coagulation changes in the cytoplasm. Loss of low-mol. components by M. lysodeikticus cells and protoplast lysis were less than in the gram-neg. microorganisms, explained by less resistance of M. lysodeikticus to decamethoxine and earlier coagulation of the cytoplasm, preventing lysis.
Mikrobiologicheskii Zhurnal (1978-1993) published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C8H8O3, Name: N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
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