Sorokin, V. A. published the artcileStudies on the complex formation of DNA with the antibacterial drug (decamethoxine), Application of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, the publication is Molekulyarnaya Biologiya (Moscow) (1990), 24(1), 214-19, database is CAplus.
The interactions of the antibacterial drug decamethoxine with natural calf thymus DNA were studied by differential UV-spectroscopy. Decamethoxine showed a nucleotide specificity. It decreased the cooperativity of melting and the thermal stability of DNA parts enriched by AT pairs. The characteristics of the helix-coil transition in the DNA parts enriched by GC-pairs were invariable. Interactions with AT-pairs resulted in their partial or complete melting at room temperature, followed by intermol. aggregation. By interacting with phosphates decamethoxine behaves not as a dication but as two single-charged ions.
Molekulyarnaya Biologiya (Moscow) published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C5H5N3S, Application of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
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