Tetrazole Ring Substitution at Carbon and Boron Sites of the Cobalt Bis(dicarbollide) Ion Available via Dipolar Cycloadditions was written by El Anwar, Suzan;Ruzickova, Zdenka;Bavol, Dmytro;Fojt, Lukas;Gruner, Bohumir. And the article was included in Inorganic Chemistry in 2020.Application In Synthesis of Tetramethylammonium chloride The following contents are mentioned in the article:
Herein, the authors describe the synthesis of two families of compounds accessible from [3 + 2] cycloaddition reactions of known B8-substituted isonitrilium and new C1-alkylnitrile and C(1,1′)-dialkylnitrile derivatives of the [(1,2-C2B9H11)2-3,3′-Co(III)]– ion with an azide ion that produce a tetrazole ring substitution at the cobaltacarborane cage. The authors outline the important differences in reactivity observed for the two types [B-isonitrilium/C-(alkyl)nitrile] of cobaltacarborane derivatives The 1st family of compounds described corresponds to C5-atom-boronated tetrazole rings, with the five-membered moiety in the 2nd type being doubly substituted at the N1 and C5 positions. This substitution opens cobaltacarborane chem. to a new type of functional group at the cage of potential utility as structural blocks for use in medicinal chem. or materials science. The study includes single-crystal x-ray structures of the starting nitriles and both families of tetrazole derivatives, and the structural features that arise from the substitutions are discussed. Herein, the authors describe the synthesis of structurally different types of tetrazole ring substitution on the Co bis(dicarbollide) ion that are accessible via [3 + 2] cycloaddition reactions of the corresponding alkylnitrile and isonitrile derivatives with an azide ion. The important differences in reactivity observed for the two types of B-isonitrilium/C-alkylnitrile derivatives of the cluster anion are demonstrated. The study is complemented with single-crystal x-ray structures of the starting nitriles and the main families of tetrazole derivatives This study involved multiple reactions and reactants, such as Tetramethylammonium chloride (cas: 75-57-0Application In Synthesis of Tetramethylammonium chloride).
Tetramethylammonium chloride (cas: 75-57-0) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Application In Synthesis of Tetramethylammonium chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics