Self-assembled core-shell clusters in deep eutectic solvents based on tetra-n-alkylammonium cations for high dissolution of strongly hydrogen-bonded small molecules was written by Jia, Jianhui;Chen, Jian-Bo;Du, Jianglong;Lian, Cheng;Xu, Silong;Liu, Honglai;Li, Shichun;Liu, Yu. And the article was included in Journal of Colloid and Interface Science in 2022.Name: Tetramethylammonium chloride The following contents are mentioned in the article:
Strongly hydrogen-bonded compounds such as 1,3,5-triamino-2,4,6-trinitrobenzene (TATB, an important insensitive high explosive) have excellent stability, but poor solubilities to limit their recrystallization, purification and recycling. In this study, core-shell clusters based on sym. tetra-n-alkylammonium [TTA]+ are designed to provide an inner cavity to incorporate TATB, and thus the clusters can sep. TATB from original hydrogen-bonded networks to increase largely the solubility Based on this design, deep eutectic solvents (DESs) based on [TTA]+ cations are first developed to yield self-assembled core-shell clusters for solubilizing TATB. Ninety-nine DESs based on [TTA]+ were prepared by combining with halide ions and hydrogen bond donors, and TATB’s solubility increases with the formation of core-shell clusters. Tetra-Bu ammonium ([TBA]+)-based DES (CS-1) displays excellent dissolution toward TATB. Room-temperature solubility of TATB in CS-1 with 32.88 mg/mL is about 10 times higher than recently reported ionic liquids and approx. 470 times higher than DMSO. Compared to traditional solvents, CS-1 shows economical and high dissolution ability toward TATB. The dissolution mechanism is demonstrated by exptl. characterizations and theor. calculations After forming Zundel-type complexes between TATB and F–, the complexes as the core are surrounded by [TBA]+ as the shell to yield core-shell clusters through self-assembly of electrostatic interaction. This study involved multiple reactions and reactants, such as Tetramethylammonium chloride (cas: 75-57-0Name: Tetramethylammonium chloride).
Tetramethylammonium chloride (cas: 75-57-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Name: Tetramethylammonium chloride
Referemce:
Chloride – Wikipedia,
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