Application of an algal growth inhibition assay to determine distribution coefficients of benzalkonium ions between kaolinite and water was written by Ndabambi, Mlamuli;Kwon, Jung-Hwan. And the article was included in Ecotoxicology and Environmental Safety in 2019.Electric Literature of C25H46ClN The following contents are mentioned in the article:
Benzalkonium compounds are widely used and found in environmental samples. Due to their amphiphilic nature, it is important to know sorption coefficients to account their bioavailability. However, currently available models describing their partitioning were developed using low mol. weight homologues and it cannot be ascertained whether they are applicable to their higher mol. weight homologues. Reasons for the scarcity of data on highly sorptive compounds include the lack of reliable quantification techniques for analyzing these chems. at environmentally relevant levels. This study, therefore, reports on an algal growth inhibition assay-based method for the determination of kaolinite/water distribution coefficients for benzalkonium compounds at their environmentally relevant concentration range. Sorption to clay was computed using the difference between median effective concentration determined in a culture with kaolinite and that derived from a culture grown in standard medium. A kinetic model was used to account for uptake into algal cells and to calculate free concentrations Due to the sensitivity of the algal species, Pseudokirchneriella subcapitata, it was possible to determine distribution coefficients below micromole per L concentrations The computed distribution coefficients showed a linear increase with number of carbon atoms in the alkyl chain up to 14. The proposed bioassay-based method should be applicable to determine distribution coefficients for highly hydrophobic chems. and ionic liquids at a concentration range lower than typical anal. limits. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Electric Literature of C25H46ClN).
N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Electric Literature of C25H46ClN
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics