Hao, Weiwei et al. published their research in Journal of Enzyme Inhibition and Medicinal Chemistry in 2017 | CAS: 95-88-5

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.SDS of cas: 95-88-5

Characterization of human S-adenosyl-homocysteine hydrolase in vitro and identification of its potential inhibitors was written by Hao, Weiwei;Li, Yanhua;Shan, Qiuli;Han, Tian;Li, Wencheng;He, Sheng;Zhu, Kongkai;Li, Yumei;Tan, Xiaojun;Gu, Jinsong. And the article was included in Journal of Enzyme Inhibition and Medicinal Chemistry in 2017.SDS of cas: 95-88-5 The following contents are mentioned in the article:

Human S-adenosyl-homocysteine hydrolase (SAHH, E.C.3.3.1.1) has been considered to be an attractive target for the design of medicines to treat human disease, because of its important role in regulating biol. methylation reactions to catalyze the reversible hydrolysis of S-adenosylhomocysteine (SAH) to adenosine (Ado) and L-homocysteine (Hcy). In this study, SAHH protein was successfully cloned and purified with optimized, Pichia pastoris (P. pastoris) expression system. The biol. activity results revealed that, among the tested compounds screened by ChemMapper and SciFinder Scholar, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenol (coniferyl alc., CAS: 458-35-5, ZINC: 12359045) exhibited the highest inhibition against rSAHH (IC50= 34 nM). Mol. docking studies showed that coniferyl alc. was well docked into the active cavity of SAHH. And several H-bonds formed between them, which stabilized coniferyl alc. in the active site of rSAHH with a proper conformation. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5SDS of cas: 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.SDS of cas: 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics