Tamima, Umme et al. published their research in Sensors and Actuators, B: Chemical in 2020 | CAS: 95-88-5

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Quality Control of 4-Chlororesorcinol

A benzo[b]xanthene-derived fluorescent probe capable of two-photon ratiometric imaging of lysosomal cysteine with high specificity was written by Tamima, Umme;Song, Chang Wook;Santra, Mithun;Reo, Ye Jin;Banna, Hasanul;Islam, Reyazul Md;Ahn, Kyo Han. And the article was included in Sensors and Actuators, B: Chemical in 2020.Quality Control of 4-Chlororesorcinol The following contents are mentioned in the article:

Cysteine, an important biothiol, is associated with diverse biol. processes, demanding efficient in vivo detection probes. Accordingly, various types of fluorescent probes have been reported so far, but still those with practical applicability are in demand. One of the challenges is how to minimize interference from other biomols. We disclose the benzoxanthene-based fluorescent probe that shows excellent substrate selectivity, and, furthermore, good ratiometric and two-photon imaging properties. The probe, which is also photostable and biocompatible, senses cysteine through very fast 1,6-conjugate addition to the benzoxanthene core, a new dipolar dye system that emits in the deep-red wavelength region. The probe enables reliable two-photon ratiometric imaging of the endogenous lysosomal cysteine. The cysteine adduct can be reverted to the probe by hydrogen peroxide most effectively among several reactive oxygen species both in solution as well as in cell. An application of the probe to quantify the cysteine level in human blood plasma is also demonstrated. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Quality Control of 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Quality Control of 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics