Chen, Gui et al. published their research in ACS Nano in 2022 | CAS: 13820-53-6

Sodium tetrachloropalladate(II) (cas: 13820-53-6) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Name: Sodium tetrachloropalladate(II)

Glutamine Antagonist Synergizes with Electrodynamic Therapy to Induce Tumor Regression and Systemic Antitumor Immunity was written by Chen, Gui;Xu, Qing;Feng, Zhenzhen;Xu, Qinqin;Zhang, Xuhui;Yang, Yuanyuan;Zhang, Yuxuan;Liang, Xing-Jie;Yu, Zhiqiang;Yu, Meng. And the article was included in ACS Nano in 2022.Name: Sodium tetrachloropalladate(II) The following contents are mentioned in the article:

Electrodynamic therapy (EDT) combining nanotechnol. with electronic current was used in this study to generate highly cytotoxic oxidative hydroxyl radicals (·OH) for tumor destruction. However, increasing evidence suggests that EDT treatment alone for one time still faces great challenges in achieving long-term tumor suppression in an immunosuppressive environment, which would raise the risk of later tumor recurrence. Benefitting from the marvelous potential of reactive oxygen species (ROS)-mediated dynamic therapies in tumor immunocombination therapy due to their immunogenic cell death (ICD) effect, a glutamine antagonist 6-diazo-5-oxo-L-norleucine (DON)-loaded nanocarrier (Pt-Pd@DON) was designed for combination therapy (EDT and immunotherapy) against tumor recurrence and metastasis. The protective immune response was motivated in highly immunosuppressive tumors by the joint functions of ICD and CD8+ T cell infiltration promoted by DON. A great therapeutic efficacy has been demonstrated in primary and metastatic tumor models, resp. This study has provided an effective thought way for clin. highly immunosuppressive tumor treatment. This study involved multiple reactions and reactants, such as Sodium tetrachloropalladate(II) (cas: 13820-53-6Name: Sodium tetrachloropalladate(II)).

Sodium tetrachloropalladate(II) (cas: 13820-53-6) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Name: Sodium tetrachloropalladate(II)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics