Octadecylamine and glucose-coderived hydrophobic carbon dots-modified porous silica for chromatographic separation was written by Chen, Jia;Yuan, Ning;Jiang, Danni;Lei, Qian;Liu, Bei;Tang, Weiyang;Row, Kyung Ho;Qiu, Hongdeng. And the article was included in Chinese Chemical Letters in 2021.Application In Synthesis of 4-Chlororesorcinol The following contents are mentioned in the article:
A Hydrophobic carbon dots (Glc-OCDs) derived from octadecylamine and glucose were successfully synthesized for the first time and then grafted onto the porous silica surface by the “Nano-on-Micro” strategy, which was served as a new stationary phase (Sil-Glc-OCDs) for reversed-phase liquid chromatog. The structure of this stationary phase was carefully verified by laser scanning confocal microscope, Fourier transform IR spectrometry, elemental anal., contact angle measurement, etc. Several analytes including seven polycyclic aromatic hydrocarbons, eight alkylbenzenes, eight phenols and seven sulfonamides can be well separated on this stationary phase. Better separation performance for certain analytes over com. C18 column was obtained. Interestingly, this stationary phase exhibited excellent chromatog. selectivity in the separation of the isomers of tert-butylbenzene, sec-butylbenzene, isobutylbenzene and n-butylbenzene. In addition, this new Sil-Glc-OCDs column was also applied for detection of calycosin-7-glucoside, ononin, calycosin, formononetin, genistein and isorhamnetin in the extract of Radix Astragali, which were found that the concentration was 0.15 g/L, 0.088 g/L, 0.14 g/L, 0.086 g/L, 0.18 g/L and 0.29 g/L, resp. We believe that this CDs-grafted silica materials are promising for chromatog. separation This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Application In Synthesis of 4-Chlororesorcinol).
4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Application In Synthesis of 4-Chlororesorcinol
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics