Simple and efficient synthetic routes to bioactive s-triazinyl dithiocarbamate derivatives was written by Desai, R. M.;Dodiya, D. K.;Trivedi, A. R.;Shah, V. H.. And the article was included in Medicinal Chemistry Research in 2008.Name: 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine The following contents are mentioned in the article:
Series of 2,4-diarylamino-6-[N-(3′-methylphenyl)dithiocarbamoyl]-s-triazines I (R = Ph, 4-ClC6H4, 2-MeOC6H4, etc.) and 2,4-bis[N-(3′-methylphenyl)dithiocarbamoyl]-6-arylamino-s-triazines II were synthesized by two different synthetic routes. In the first route (A), 2,4,6-trichloro-s-triazine (III) was condensed with N-(3-methylphenyl)ammoniumdithiocarbamate to afford compounds IV [X = Cl, SC(:S)NHC6H4-Me-3], which on reaction with different aryl amines afforded compounds I or II. In the second route (B), condensation of III with different aryl amines yielded compounds V (Y = Cl, NHR). On further treatment with N-(3-methylphenyl)ammoniumdithiocarbamate these afforded compounds I or II. The newly synthesized compounds I and II were characterized by elemental analyses, IR (IR), and 1H NMR (NMR) spectroscopic investigation. All the products were evaluated for their antibacterial and antifungal activity. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Name: 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine).
4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Name: 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics