Golpayegani, Mohammad Reza et al. published their research in RSC Advances in 2022 | CAS: 5137-55-3

N-Methyl-N,N-dioctyloctan-1-aminium chloride (cas: 5137-55-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).COA of Formula: C25H54ClN

Sensitive determination of vincristine in plasma of children with leukaemia using vortex-assisted dispersive liquid-liquid microextraction based on hydrophobic deep eutectic solvent was written by Golpayegani, Mohammad Reza;Akramipour, Reza;Gheini, Simin;Amini, Mazyar Vakili;Fattahi, Farshad;Mohebbi, Ali;Fattahi, Nazir. And the article was included in RSC Advances in 2022.COA of Formula: C25H54ClN The following contents are mentioned in the article:

Vincristine has a wide spectrum of clin. activity and is currently used in the treatment of leukemia. Despite its high therapeutic properties, vincristine has common side effects. Accordingly, it is desirable to determine vincristine in plasma for the use of the drug with strict monitoring. In the present research, for the first time a hydrophobic deep eutectic solvent (DES) composed of methyltrioctylammonium chloride (MTOAC) and n-butanol in a molar ratio of 1 : 3 was used as the extractant in dispersive liquid-liquid microextraction (DLLME) for the extraction and determination of vincristine in the plasma of children with leukemia prior to its anal. by high-performance liquid chromatog.-UV detection (HPLC-UV). Under optimal exptl. conditions, the method showed good linearity with a correlation coefficient (R2) of 0.9986 in the linear range of 0.06-300 μg L-1, low limit of detection of 0.02 μg L-1 and acceptable extraction efficiency (EE) of 88.4%. In the final stage of the study, this proposed technique was successfully applied to determine vincristine in real plasma, and the obtained results demonstrated the ability of the synthesized DES to extract drugs from biol. fluids. This study involved multiple reactions and reactants, such as N-Methyl-N,N-dioctyloctan-1-aminium chloride (cas: 5137-55-3COA of Formula: C25H54ClN).

N-Methyl-N,N-dioctyloctan-1-aminium chloride (cas: 5137-55-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).COA of Formula: C25H54ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics