Microwave assisted synthesis and in vitro antimicrobial assessment of quinolone based s-triazines was written by Patel, Divyesh;Patel, Rahul;Kumari, Premlata;Patel, Navin. And the article was included in Heterocyclic Communications in 2011.Computed Properties of C9H6Cl2N4 The following contents are mentioned in the article:
A series of 1,3,5-triazine derivatives that contain aniline, 4-hydroxy-N-methylquinolone and different piperazine and piperidine moieties as substituents on the carbon atoms of the triazine ring was synthesized by a simple and efficient synthetic protocol. Comparative studies were performed on the compounds, which were synthesized with conventional and microwave heating methods. The microwave method is more beneficial as it provides an increase in yield and 90%-95% reduction time. The antimicrobial activity of the compounds was tested against seven bacteria (Staphylococcus aureus, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Salmonella typhi, Proteus vulgaris) and two fungi (Aspergillus niger, Candida albicans). Some of the novel s-triazines noteworthy activity in MIC and agar diffusion tests. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Computed Properties of C9H6Cl2N4).
4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Computed Properties of C9H6Cl2N4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics