The Regioselective Arylation of 1,3-Benzodioxoles was written by Kanai, Yuki;Mueller-Borges, Dorian;Plenio, Herbert. And the article was included in Advanced Synthesis & Catalysis in 2022.Application In Synthesis of Sodium tetrachloropalladate(II) The following contents are mentioned in the article:
The direct arylation of 1,3-benzodioxole and 2,2-difluorobenzo[1,3]dioxole with different aryl bromides RBr (R = 4-methylphenyl, naphthalen-1-yl, 9,9-diethyl-9H-fluoren-2-yl, etc.) yields the resp. 4-substitued products I (R1 = H, F) in yields of >80% requiring between 0.05-1 mol% Na2PdCl4, 30 mol% pivalic acid, 1.3 equivalents K2CO3 and ca. 250 equivalents of diethylacetamide per Pd at T = 120°C. The nature of the amide and the concentration of the reactants are crucial for the optimization of the reaction conditions. The primary role of the acetamide is that of a ligand to Pd, it is not needed as a solvent. This study involved multiple reactions and reactants, such as Sodium tetrachloropalladate(II) (cas: 13820-53-6Application In Synthesis of Sodium tetrachloropalladate(II)).
Sodium tetrachloropalladate(II) (cas: 13820-53-6) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Application In Synthesis of Sodium tetrachloropalladate(II)
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics