Base-Promoted Reactions of Organostibines with Alkynes and Organic Halides to Give Chalcogenated (Z)-Olefins and Ethers was written by Le, Liyuan;Li, Shuangshuang;Zhang, Dejiang;Yin, Shuang-Feng;Kambe, Nobuaki;Qiu, Renhua. And the article was included in Organic Letters in 2022.Quality Control of 1-Bromo-6-chlorohexane The following contents are mentioned in the article:
Herein, with air-stable chalcogenated stibines (Sb-ER) as organometallic chalcogenating reagents, base-promoted (Z)-hydrochalcogenation of alkynes with DMSO/DMSO-d6 as hydrogen/deuterium sources, giving chalcogenated (Z)-olefins in good yields and with excellent regioselectivity was developed. These reagents, easily synthesized from halostibines with in situ generated [Zn(ER)2] at room temperature within a few minutes, was also used in the base-promoted C(sp3)-S(Se) cross-coupling with C(sp3)-X and copper-catalyzed C(sp2)-S(Se) cross-coupling with C(sp2)-X (X = F, CI, Br, I) under mild conditions. This protocol was also be simply extended to organobismuth complexes (Bi-ER) with good functional tolerance. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Quality Control of 1-Bromo-6-chlorohexane).
1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Quality Control of 1-Bromo-6-chlorohexane
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics