Method of splitting key intermediate of clopidogrel was written by Xu, Han-qing. And the article was included in Guangzhou Huagong in 2014.Recommanded Product: 141109-14-0 The following contents are mentioned in the article:
The racemic 2-(2-chlorophenyl)glycine as the starting material, through esterification to give racemic 2-(2-chlorophenyl)glycine Me ester, resolved by (L)-(+)-tartrate, Bu ketone as solvent, (S)-(+)-2-(2-chlorophenyl)glycine Me ester was obtained, and the solvent recovery yield was more than 95%. This study involved multiple reactions and reactants, such as (S)-Methyl 2-amino-2-(2-chlorophenyl)acetate (cas: 141109-14-0Recommanded Product: 141109-14-0).
(S)-Methyl 2-amino-2-(2-chlorophenyl)acetate (cas: 141109-14-0) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Recommanded Product: 141109-14-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics