Guo, Zhiqiang’s team published research in Bioorganic & Medicinal Chemistry Letters in 15 | CAS: 854778-30-6

Bioorganic & Medicinal Chemistry Letters published new progress about 854778-30-6. 854778-30-6 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (2-Chloro-3-methoxyphenyl)boronic acid, and the molecular formula is C7H8BClO3, SDS of cas: 854778-30-6.

Guo, Zhiqiang published the artcileUracils as potent antagonists of the human gonadotropin-releasing hormone receptor without atropisomers, SDS of cas: 854778-30-6, the publication is Bioorganic & Medicinal Chemistry Letters (2005), 15(10), 2519-2522, database is CAplus and MEDLINE.

Uracil derivatives I [X1 = F, CF3; X2 = F, SO2Me, Cl, MeS, etc.; Y = 2-F-3-OMe, 2-Cl, H, 2-F, etc.] were designed and synthesized to avoid atropisomers observed in the 6-methyluracils as antagonists of the human GnRH receptor. Optimization at the 1- and 5-positions of the uracil resulted in potent compounds such as I [X1 = F, X2 = CF3, Y = 2-Cl-3-OMe] (Ki = 0.45 nM).

Bioorganic & Medicinal Chemistry Letters published new progress about 854778-30-6. 854778-30-6 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (2-Chloro-3-methoxyphenyl)boronic acid, and the molecular formula is C7H8BClO3, SDS of cas: 854778-30-6.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics