Hsu, Li-Na published the artcileCentral action of drugs for treatment of hypertension. I. Effect of reserpine on the conditioned response and blood pressure of normal dogs, Category: chlorides-buliding-blocks, the publication is Shengli Xuebao (1961), 24(3-4), 151-60, database is CAplus.
In 7 normal dogs given reserpine orally at 0.005-0.03 mg./kg. for 4-15 days, the positive conditioned response decreased and the reinforcement relation changed, sometimes with change in phase. The effect on the delayed conditioned response depends on dosage. A large dose (0.25 mg./kg.) seriously upset the equilibrium in stimulation-depression mechanisms to cause a nervous condition. With a daily dose of 0.005 or 0.01 mg./kg., no change in blood pressure was observed, but a change in conditioned response was quite distinct. This indicates that the cerebral cortex is more sensitive to resperine than the midbrain. It also indicates that the change in response is not induced by the action of resperine on the vasomotor center.
Shengli Xuebao published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, Category: chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics