Enantioselective Synthesis of Isoquinolines: Merging Chiral-Phosphine and Gold Catalysis was written by Gao, Yu-Ning;Shi, Feng-Chen;Xu, Qin;Shi, Min. And the article was included in Chemistry – A European Journal in 2016.Formula: C15H9ClO The following contents are mentioned in the article:
The highly enantioselective synthesis of dihydroisoquinoline derivatives from aromatic sulfonated imines tethered with an alkyne moiety, through a one-pot asym. relay catalysis of chiral-phosphine and gold catalysts, is reported. Enantiomerically enriched dihydroisoquinoline derivatives were afforded in good yields and good-to-excellent ee values under mild conditions, based on the asym. aza-Morita-Baylis-Hillman reaction. Dihydroisoquinoline derivatives containing two chiral centers were also synthesized through further transformations. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Formula: C15H9ClO).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Formula: C15H9ClO
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics