Merging Gold and Organocatalysis: A Facile Asymmetric Synthesis of Annulated Pyrroles was written by Hack, Daniel;Loh, Charles C. J.;Hartmann, Jan M.;Raabe, Gerhard;Enders, Dieter. And the article was included in Chemistry – A European Journal in 2014.Reference of 1186603-47-3 The following contents are mentioned in the article:
The combination of cinchona-alkaloid-derived primary amine and AuI-phosphine catalysts allowed the selective C-H functionalization of two adjacent carbon atoms of pyrroles under mild reaction conditions. This sequential dual activation provides seven-membered-ring-annulated pyrrole derivatives in excellent yields and enantioselectivities. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Reference of 1186603-47-3).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Reference of 1186603-47-3
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics