Synthesis of isomer of clopidogrel was written by Li, Dong-xing;Pu, Tong;Zhong, Wei-hui. And the article was included in Zhejiang Huagong in 2010.Related Products of 141109-14-0 The following contents are mentioned in the article:
The Me 2-(2-chlorophenyl)-2-(4,5-dihydrothieno [2,3-c]-pyridin-6 (7H)-yl)acetate, an isomer of clopidogrel, was achieved from 2-chlorophenylglycine Me ester and 2-(3-thiophenyl)ethyl para-toluenesulfonate via amino substitution, Mannich reaction and formation of sulfate salt in 56%. The advantages of our method are com. available starting materials, mild reaction condition and high yield. This study involved multiple reactions and reactants, such as (S)-Methyl 2-amino-2-(2-chlorophenyl)acetate (cas: 141109-14-0Related Products of 141109-14-0).
(S)-Methyl 2-amino-2-(2-chlorophenyl)acetate (cas: 141109-14-0) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Related Products of 141109-14-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics